My PhD

My PhD was focused on modelling the developing sleep patterns in infancy and early childhood using a model of the subcortical sleep-wake switch. Using publically available longitudinal data, I modelled the trajectory of physiologically based parameters reflecting the circadian and sleep homeostatic drives over infancy in individuals. With a Bayesian model, I estimated distributions of parameters that aligned with the distribution of sleep patterns observed in infancy and early childhood. I expanded on the sleep-wake model to include a REM-NREM switch, and used that model to explore what physiological changes could explain the unique sleep architecture in infancy.

I have one manuscript submitted and currently available as a preprint. My thesis was submitted on the 28/11/2023.